Glossary

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  • ADCAntibody-Drug Conjugates
  • AntigenThe part of a pathogen that stimulates a response from the immune system.
  • Area Under the CurveIn the field of pharmacokinetics, the Area Under the Curve (AUC) has a specific meaning. It is the region under a plotted line in a graph of medicine concentration in blood plasma over time. Typically, the area is calculated starting from the time the medicine is administered until the time(...)
  • AUCIn the field of pharmacokinetics, the Area Under the Curve (AUC) has a specific meaning. It is the region under a plotted line in a graph of medicine concentration in blood plasma over time. Typically, the area is calculated starting from the time the medicine is administered until the time(...)
  • ArmIn clinical research this refers to any of the treatment groups in a randomised trial. Many randomised trials have two ‘arms’ or groups, but some may have three or even more.
  • AttritionAttrition is the loss of participants during a clinical trial; it is also known as the 'drop-out rate'. The opposite of attrition is 'retention'. Attrition can cause bias in study results if more participants drop out of one study arm than another, or if there is a difference between the(...)
  • AuditAudits (independent evaluations of activities, processes and product quality) are an element of quality management in industry, finance, commerce and public service. They are typically performed by an independent auditing service, but may also be conducted as an internal audit(...)
  • AutologousAutologous tissue or cells are tissue or cells derived from the same individual. For example, skin transferred from one part of the body to another is autologous tissue; in advanced therapies, stem cells are removed, stored, and later given back to the same person. Autologous transplants are(...)
  • Autoridade Nacional do Medicamento e Produtos de SaúdePortuguese National Competent Authority. http://www.infarmed.pt"
  • INFARMEDPortuguese National Competent Authority. http://www.infarmed.pt"

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