Glossary

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  • AB
    An antibody (AB), also known as an immunoglobin, is a protein produced by the body's immune system when it detects harmful substances (called antigens). Antigens can be molecules from microorganisms (bacteria, fungi, parasites, and viruses), or chemicals (insect venom). Antibodies recognise(...)
  • ACS
    Sets of data from individuals in a trial are given unique codes so they can be stored and managed properly. Anonymous coding systems (ACS) use codes that do not relate to personal information that might be used to identify the individual in any way (for example, a participant's initials or(...)
  • ADC
    Antibody-Drug Conjugates
  • Anonymous coding systems
    Sets of data from individuals in a trial are given unique codes so they can be stored and managed properly. Anonymous coding systems (ACS) use codes that do not relate to personal information that might be used to identify the individual in any way (for example, a participant's initials or(...)
  • Anthropology
    The scientific study of the social, cultural and physical development of humans, past and present.
  • Antibody
    An antibody (AB), also known as an immunoglobin, is a protein produced by the body's immune system when it detects harmful substances (called antigens). Antigens can be molecules from microorganisms (bacteria, fungi, parasites, and viruses), or chemicals (insect venom). Antibodies recognise(...)
  • Antibody-Drug Conjugates
    Antibody-Drug Conjugates
  • Antigen
    The part of a pathogen that stimulates a response from the immune system.
  • Area Under the Curve
    In the field of pharmacokinetics, the Area Under the Curve (AUC) has a specific meaning. It is the region under a plotted line in a graph of medicine concentration in blood plasma over time. Typically, the area is calculated starting from the time the medicine is administered until the time(...)
  • Arm
    In clinical research this refers to any of the treatment groups in a randomised trial. Many randomised trials have two ‘arms’ or groups, but some may have three or even more.
  • Attrition
    Attrition is the loss of participants during a clinical trial; it is also known as the 'drop-out rate'. The opposite of attrition is 'retention'.Attrition can cause bias in study results if more participants drop out of one study arm than another, or if there is a difference between the(...)
  • AUC
    In the field of pharmacokinetics, the Area Under the Curve (AUC) has a specific meaning. It is the region under a plotted line in a graph of medicine concentration in blood plasma over time. Typically, the area is calculated starting from the time the medicine is administered until the time(...)
  • Autologous
    Autologous tissue or cells are tissue or cells derived from the same individual. For example, skin transferred from one part of the body to another is autologous tissue; in advanced therapies, stem cells are removed, stored, and later given back to the same person. Autologous transplants are(...)
  • Autoridade Nacional do Medicamento e Produtos de Saúde
    Portuguese National Competent Authority. http://www.infarmed.pt"
  • INFARMED
    Portuguese National Competent Authority. http://www.infarmed.pt"

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