Omics technologiesThe 'Omics technologies are relatively recent fields of study such as genomics, proteomics, or metabolomics. They deal with large amounts of data because they assess entire genomes, proteomes, or metabolomes. Information technology (IT) is therefore a crucial element in 'omics research.
OncogeneAn oncogene is a mutated gene that contributes to the development of a cancer. In their normal, non-mutated state, oncogenes are called proto-oncogenes, and they are important in the regulation of cell growth. When altered, an oncogene can either promote or allow the uncontrolled growth of(...)
Orodispersible tabletA tablet designed to be dissolved in the mouth rather than swallowed whole.
Orphan designationOrphan designation is a special status for a medicine used to treat a rare disease or condition. An orphan designation is adopted by the Committee for Orphan Medicinal Products (COMP) of the European Medicines Agency (EMA) and confirmed by the European Commission (EC) before the granting of(...)
Orphan medicineAn orphan medicine is a medicine that has been developed specifically to treat a rare condition (an ‘orphan disease’). Orphan medicines generally follow the same regulatory development path as any other medicine, however, some incentives are provided to encourage a manufacturer to invest in(...)
OGYÉINational Institute of Pharmacy and Nutrition; Hungarian National Competent Authority. https://www.ogyei.gov.hu"
OutlierIn statistics, an outlier is an observation point that is distant from other observations, i.e. some data points will be further away from the sample mean than what is deemed reasonable. An outlier may be due to variability in the measurement or it may indicate experimental error; the latter(...)
Over expressionOver expression is when a gene is too active and produces too much of the protein it encodes. Normally a variety of molecular mechanisms ensures that genes are expressed at the appropriate levels at the right times. Many cancers arise through the over expression of key regulatory genes.
