Recombinant GeneA recombinant gene is one which has been changed by the addition and/or removal of some of its sequence. This can happen naturally or may be done artificially in the laboratory.Natural recombination happens when the chromosomes in parents interact and exchange genetic material so that their(...)
Recombinant vaccineA vaccine using an antigen produced using recombinant DNA technology.
RecruitmentRecruitment is the process used by investigators to enrol people (participants) into a clinical study. Recruitment is based on the inclusion and exclusion criteria that are documented in the study protocol.
RecurrenceRecurrence is the return of a sign, symptom, or disease after some time when the signs or symptoms could not be detected. It is applied to the return of symptoms of an incurable disease. For example, the reappearance of cancer cells at the same site as the original tumour, or in another(...)
Reference medicineWhen talking about biosimilar and generic medicines, a reference medicine is the existing medicine already on the market that biosimilar and generic medicines are developed to be similar to or copies of, respectively.
Regulatory affairsRegulatory affairs is a relatively new profession which developed from the desire of governments to protect public health by controlling the safety and efficacy of products in areas including human medicines, veterinary medicines, medical devices, pesticides, agrochemicals, cosmetics and(...)
ReimbursementIn clinical research, is the economic compensation for legitimate expenses incurred by a participant taking part in a specific research project.
Relative clinical effectivenessIt can be defined as the extent to which an intervention does more good than harm compared to one or more alternative interventions for achieving the desired results, when provided under the usual circumstances of health care practice.
Relative efficacyIt is the extent to which an intervention does more good than harm compared to one or more alternative interventions, when provided under ideal circumstances.
ReliabilityThe reliability of a measurement or tool is how consistent it is. A reliable measurement or tool will give the same result when repeated at random in the same patient or sample. In clinical trials, reliability is an important consideration in the choice of primary outcome measures (such as an(...)
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