Glossary

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  • Time-to-event endpointA time-to-event endpoint is the time taken until a pre-defined event takes place, once groups in a trial start to receive treatment or placebo. There are several kinds of time-to-event endpoints. For example, time-to-progression (TTP) is the time between randomisation of people to groups(...)
  • TTPTime-to-Progress
  • Time-to-ProgressTime-to-Progress
  • TEPTissue Engineered Product; Tissue Engineered Medicine
  • Tissue Engineered Product; Tissue Engineered MedicineTissue Engineered Product; Tissue Engineered Medicine
  • TolerabilityThe tolerability of the medicinal product represents the degree to which adverse effects can be 'tolerated' or accepted by a patient.
  • ToxicityToxicity is the degree to which a chemical or biological substance can damage a living organism. It can refer to harm to specific organs, tissues or cells, or to the whole organism.Medicines development is a step-by-step process involving the evaluation of both animal and human safety(...)
  • ToxicokineticsA specific type of pharmacokinetics that studies what the body does to a medicinal product at toxic doses. These studies assess how a substance enters the body and what happens to it in the body depending on the absorption, distribution, metabolism and excretion of the substance. Toxicokinetic(...)
  • ToxicologyToxicology is the study of the toxic effects of substances on living organisms. It includes symptoms, mechanisms, treatments and detection of poisoning, especially the poisoning of people. The main criterion regarding the toxicity of a substance is the dose, i.e. the amount of exposure to the(...)
  • Toxoid vaccineToxoid vaccines use an inactivated toxin of a pathogenic micro-organism to stimulate a response by the immune system.

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