Genomic technologiesGenomic technologies are those new methods, technologies, and instruments used to study and manipulate the genome.
GenomicsGenomics is the branch of biology that studies the entire genome of an organism by sequencing, assembling, and analysing the function and structure of its DNA. Advances in genomics have allowed great progress to be made in understanding diverse illnesses.Genomics research can develop more(...)
Genotoxicity StudyA genotoxicity study is designed to detect compounds that cause genetic damage either directly or indirectly in cells exposed to the toxic substrates. Genotoxicity studies may be performed in vitro or in vivo.Compounds which are positive in tests that detect such damage have the potential to(...)
GenotoxinA chemical or other agent that provokes a harmful change in a person’s genetic material regardless of the mechanism by which the change is induced. A genotoxin can cause mutations in DNA (a mutagen), it can trigger cancer (a carcinogen), or it can cause a birth defect (a teratogen).
GenotypeThe genotype is an individual's collection of genes, including which genetic variants they have. It is the entire complex of genes inherited from both parents. The genotype determines the hereditary characteristics of an individual. A genotype can be determined by sequencing an individual™s genome.
GenotypingGenotyping is the process of determining differences in the genetic make-up or genotype of an individual by examining their individual DNA sequence. This can be done by comparing one person's genotype to another individual's sequence, or against a reference sequence.
Gold StandardIn medicines development, the gold standard often refers to the best available therapy/product/treatment. Depending on the context, the gold standard may also mean different things. In clinical design, a double-blind, randomisedtrial is seen by many as the gold standard.The gold standard may(...)
Good Clinical PracticeGood Clinical Practice (GCP) is an international ethical and scientific quality standard for designing, conducting, recording and reporting clinical trials that involve human participants. The International Conference on Harmonisation (ICH) has issued a guideline with the objective to provide(...)
GCPGood Clinical Practice (GCP) is an international ethical and scientific quality standard for designing, conducting, recording and reporting clinical trials that involve human participants. The International Conference on Harmonisation (ICH) has issued a guideline with the objective to provide(...)
Good Distribution PracticeGood Distribution Practice (GDP) is a standard ensuring that the quality of a medicine is maintained throughout the distribution network, so that authorised medicines are distributed to retail pharmacists and others selling medicines to the general public without any alteration of their properties.
