Setting the ‘first-in-human’ dose Medicines R&D Careful consideration of various factors is necessary before progressing from non-clinical to clinical studies and setting the first-in-human dose. Read more »
Making a medicine. Step 6: Phase I – Proof of mechanism Medicines R&D Phase I clinical studies, or proof of mechanism studies, test the safety of a medicine in humans. Usually, these studies are carried out in healthy human volunteers. Read more »
