Biotechnology

Non-clinical studies can be performed at any time during the life-cycle of the product, testing the compound outside of humans. Non-clinical studies aim to identify candidate therapies with the greatest probability of success, assess safety, and build solid scientific foundations before the transition to clinical development phases.

During lead generation, many molecules are tested for target interaction. These may then need to be altered, or optimised, in order to improve their effect on the target.

The animal models used in non-clinical trials are carefully selected, taking various factors into consideration.

A rigorous non-clinical programme must be completed before a medicine may be tested in humans for the first time in Phase I clincial trials.